Breast Cancer Screening in Men

Аннотация

Breast cancer screening has been highly successful in women in reducing mortality through early
detection. In comparison, clinical detection of breast cancer remains the norm in men, and delay
in diagnosis is reflected by a persistent survival disparity compared to women despite advances
in modern therapy. Male breast cancer presents an interesting dilemma. While mammography
is highly sensitive and specific for male breast cancer, routine screening is not justified by the
overall low disease incidence. Yet there has been interest in leveraging mammography in targeted
screening of men with identifiable risk factors to allow early detection, and early data may support
this approach. The purpose of this article is to explore the potential utility of targeted breast cancer
screening in men by examining unique clinical and biologic characteristics of male breast cancers
that may lend themselves to mammographic detection. We will also discuss available evidence in
screening outcomes in men and summarize recent updates in risk management recommendations
in Society guidelines.